JW67
Cat. No.:YN450217
CAS No. :442644-28-2
产品名称: | JW67 |
CAS No.: | 442644-28-2 |
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分子量: | 394.38 |
分子式: | C21H18N2O6 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | JW67 抑制典型Wnt信号,其IC50值为 1.17 μM。JW67 影响由 β- 连环蛋白/GSK-3β/AXIN/APC/CK1 组成的多蛋白复合物,该复合物可快速降低活性 β- 连环蛋白,随后下调Wnt靶基因。JW67 也抑制结直肠癌细胞生长。 |
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