GLI antagonist-1
Cat. No.:YN450220
产品名称: | GLI antagonist-1 |
CAS No.: | 599150-20-6 |
Chemical Name: | |
Synonyms: | 2-Methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphe nyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinolin;2-Methoxyethyl 4-(3-hydroxyphenyl)-7-(2-methoxyphe nyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline;HPI 1;HPI-1;0130970;2-METHOXYETHYL 1,4,5,6,7,8-HEXAH |
分子量: | 419.512767553329 |
分子式: | C26H29NO4 |
SMILES: | COCCN1C2=C(C(=O)CC(C3C=CC=CC=3OC)C2)C(C2C=CC=C(O)C=2)C=C1C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GLIantagonist-1 是一种有效的GLI拮抗剂,IC50值为 1.1 µM。GLIantagonist-1 显示出抗增殖活性。GLIantagonist-1 降低 GLI1 mRNA 表达。GLIantagonist-1 以剂量依赖性方式抑制集落形成。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |