B-Raf IN 11
Cat. No.:YN350357
CAS No. :918504-27-5
产品名称: | B-Raf IN 11 |
CAS No.: | 918504-27-5 |
Chemical Name: | |
Synonyms: | |
分子量: | 458.28 |
分子式: | C17H14BrF2N3O3S |
SMILES: | FC1=C(C(C2=CNC3=NC=C(Br)C=C32)=O)C(F)=C(NS(=O)(CCC)=O)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | B-Raf IN 11 (ZINC72115182) 是一种选择性的B-RafV600E抑制剂 (IC50=76 nM),其对 B-RafV600E的选择性高于 B-RafWT,选择性为 3.1 倍,可用于结直肠癌的研究。 |
IC50和靶点: | [{name:"B-RafV600E:76 nM (IC50)"},{name: "BRAFWT:238 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |