Calcitriol
Cat. No.：YN370005
CAS No. ：32222-06-3
| 产品名称: | Calcitriol |
| CAS No.: | 32222-06-3 |
| Chemical Name: | (1R,3S,5Z)-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol |
| Synonyms: | 骨化三醇; 1,25-Dihydroxyvitamin D3 |
| 分子量: | 416.64 |
| 分子式: | C₂₇H₄₄O₃ |
| SMILES: | C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](CCCC(C)(O)C)C)CCC/2)[H])O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Calcitriol 是活性最大的 vitamin D 代谢物，也是 vitamin D 受体 (VDR) 的激动剂。 |
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Lawson, D.E., Fraser, D.R., Kodicek, E., et al.Identification of 1,25-dihydroxycholecalciferol, a new kidney hormone controlling calcium metabolismNature230(5291),228-230(1971)
Haussler, M.R., Zerwekh, J.E., Hesse, R.H., et al.Biological activity of 1α-hydroxycholecalciferol, a synthetic analog of the hormonal form of vitamin D3Proc. Natl. Acad. Sci. USA70(8),2248-2252(1973)
Binderup, L., Latini, S., Binderup, E., et al.20-epi-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responsesBiochem. Pharmacol.42(8),1569-1575(1991)
Canalejo, A., Almadén, Y., Torregrosa, V., et al.The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosisJ. Am. Soc. Nephrol.11(10),1865-1872(2000)
