Cyclo(his-pro)
Cat. No.：YN370152
CAS No. ：53109-32-3
| 产品名称: | Cyclo(his-pro) |
| CAS No.: | 53109-32-3 |
| Chemical Name: | (3S,8aS)-hexahydro-3-(1H-imidazol-4-ylmethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione |
| Synonyms: | Cyclo(histidyl-proline); Histidylproline diketopiperazine |
| 分子量: | 234.25 |
| 分子式: | C₁₁H₁₄N₄O₂ |
| SMILES: | O=C(N[C@H]1CC2=CN=CN2)[C@@](CCC3)([H])N3C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cyclo(his-pro) (Cyclo(histidyl-proline)) 是一种具有口服活性的，结构上与促甲状腺激素释放激素相关的环状二肽。Cyclo(his-pro) 可以抑制NF-κB核积累。Cyclo(his-pro) 可以穿越脑血屏障并影响多种炎症和应激反应。 |
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Prasad, C.Neurobiology of cyclo(His-Pro)Ann. N. Y. Acad. Sci.553(1),232-251(1989)
Grottelli, S., Ferrari, I., Pietrini, G., et al.The role of cyclo(His-Pro) in neurodegenerationInt. J. Mol. Sci.17(8),1332(2016)
Prasad, C., Matsui, T., and Peterkofsky, A.Antagonism of ethanol narcosis by histidyl-proline diketopiperazineNature268(5616),142-144(1977)
