L-Sepiapterin
Cat. No.:YN370567
CAS No. :17094-01-8
产品名称: | L-Sepiapterin |
CAS No.: | 17094-01-8 |
Chemical Name: | Sepiapterine; 2-Amino-7,8-dihydro-6-[(2S)-2-hydroxy-1-oxopropyl]-4(3H)-pteridinone |
Synonyms: | Sepiapterin |
分子量: | 237.22 |
分子式: | C₉H₁₁N₅O₃ |
SMILES: | O=C1NC(N)=NC2=C1N=C(C([C@@H](O)C)=O)CN2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | L-Sepiapterin (Sepiapterin) 是内皮型一氧化氮合酶 (eNOS) 辅因子四氢生物喋呤 (BH4) 的前体。L-Sepiapterin 改善 db/db 小鼠肠系膜小动脉内皮功能障碍,诱导血管生成。L-Sepiapterin 通过下调 p70S6K依赖性 VEGFR-2 表达抑制卵巢癌细胞增殖和迁移。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Pannirselvam, M., et al.: Br. J. Pharmacol., 140, 701 (2003)
Bagi, Z., et al.: J. Vasc. Res., 40, 47 (2003)
Sawabe, K., et al.: J. Pharmacol. Sci., 96, 124 (2004)