Epipregnanolone
Cat. No.：YN370617
CAS No. ：128-21-2
| 产品名称: | Epipregnanolone |
| CAS No.: | 128-21-2 |
| Chemical Name: | (5β)-3β-hydroxy-pregnan-20-one |
| Synonyms: | |
| 分子量: | 318.49 |
| 分子式: | C₂₁H₃₄O₂ |
| SMILES: | CC([C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Epipregnanolone是一种内源性神经甾体，具有催眠和镇静作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Prince, R.J., and Simmonds, M.A.5β-pregnan-3β-ol-20-one, a specific antagonist at the neurosteroid site of the GABAA receptor-complexNeurosci. Lett.135(2),273-275(1992)
Hill, M., Cibula, D., Havlíkova, H., et al.Circulating levels of pregnanolone isomers during the third trimester of human pregnancyJ. Steroid Biochem. Mol. Biol.105(1-5),166-175(2007)
Perusquía, M., and Jasso-Kamel, J.Influence of 5α- and 5β-reduced progestins on the contractility of isolated human myometrium at termLife Sci.68(26),2933-2944(2001)
O'Dell, L.E., Purdy, R.H., Covey, D.F., et al.Epipregnanolone and a novel synthetic neuroactive steroid reduce alcohol self-administration in ratsPharmacol. Biochem. Behav.81(3),543-550(2005)
