Tetrahydrocortisone
Cat. No.:YN370647
产品名称: | Tetrahydrocortisone |
CAS No.: | 53-05-4 |
Chemical Name: | (3α,5β)-3,17,21-trihydroxy-pregnane-11,20-dione |
Synonyms: | |
分子量: | 364.48 |
分子式: | C₂₁H₃₂O₅ |
SMILES: | C[C@@]1([C@]([H])([C@]2([C@]([H])3[C@]4(C)[C@]([H])(CC2)C[C@@H](CC4)O)[H])CC[C@@]1(C(CO)=O)O)CC3=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tetrahydrocortisone 是一种应激性激素,也是由 5-还原酶还原 Cortisone 而产生的 Cortisone 尿代谢物。 |
IC50和靶点: | |
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Abel, S.M., Maggs, J.L., Back, D.J., et al.Cortisol metabolism by human liver in vitro—I. Metabolite identification and inter-individual variabilityJ. Steroid. Biochem. Mol. Biol.43(7),713-719(1992)
White, P.C., Mune, T., and Agarwal, A.K.11β-hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excessEndocr. Rev.18(1),135-156(1997)