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Hydroxycotinine

Cat. No.:YN370686

  • CAS No. :34834-67-8

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    • 参考文献
    • 产品名称: Hydroxycotinine
      CAS No.: 34834-67-8
      Chemical Name: 3R-hydroxy-1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone
      Synonyms:
      分子量:192.21
      分子式:C₁₀H₁₂N₂O₂
      SMILES:O=C1N(C)[C@H](C2=CC=CN=C2)C[C@H]1O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Hydroxycotinine 是一种尼古丁代谢物,在吸烟者尿液中常见。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Zhu, A.Z., Zhou, Q., Cox, L.S., et al.Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intakePLoS One8(8),e70938(2013)

      von Weymarn, L.B., Retzlaff, C., and Murphy, S.E.CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ionJ. Pharmacol. Exp. Ther.343(2),307-315(2012)

      Murphy, S.E., Wickham, K.M., Lindgren, B.R., et al.Cotinine and trans 3'-hydroxycotinine in dried blood spots as biomarkers of tobacco exposure and nicotine metabolismJ. Expo. Sci. Environ. Epidermiol.23(5),513-518(2013)

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