Hydroxycotinine
Cat. No.:YN370686
CAS No. :34834-67-8
产品名称: | Hydroxycotinine |
CAS No.: | 34834-67-8 |
Chemical Name: | 3R-hydroxy-1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone |
Synonyms: | |
分子量: | 192.21 |
分子式: | C₁₀H₁₂N₂O₂ |
SMILES: | O=C1N(C)[C@H](C2=CC=CN=C2)C[C@H]1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Hydroxycotinine 是一种尼古丁代谢物,在吸烟者尿液中常见。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
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Zhu, A.Z., Zhou, Q., Cox, L.S., et al.Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intakePLoS One8(8),e70938(2013)
von Weymarn, L.B., Retzlaff, C., and Murphy, S.E.CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ionJ. Pharmacol. Exp. Ther.343(2),307-315(2012)
Murphy, S.E., Wickham, K.M., Lindgren, B.R., et al.Cotinine and trans 3'-hydroxycotinine in dried blood spots as biomarkers of tobacco exposure and nicotine metabolismJ. Expo. Sci. Environ. Epidermiol.23(5),513-518(2013)