8-Hydroxyguanosine
Cat. No.：YN370693
CAS No. ：3868-31-3
| 产品名称: | 8-Hydroxyguanosine |
| CAS No.: | 3868-31-3 |
| Chemical Name: | 7,8-dihydro-8-oxo-guanosine |
| Synonyms: | |
| 分子量: | 299.24 |
| 分子式: | C₁₀H₁₃N₅O₆ |
| SMILES: | OC[C@@H]1[C@H]([C@H]([C@H](N2C(NC3=C2N=C(N)NC3=O)=O)O1)O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 8-Hydroxyguanosine 是氧化应激的系统标记，也可用作氢氧自由基对 RNA 损伤的标记。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Wu, J., and Li, Z.Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stressBiochem. Biophys. Res. Commun.372(2),288-292(2008)
Nunomura, A., Perry, G., Pappolla, M.A., et al.RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's diseaseJ. Neurosci.19(6),1959-1964(1999)
Zhang, J., Perry, G., Smith, M.A., et al.Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neuronsAm. J. Pathol.154(5),1423-1429(1999)
