7-Dehydrocholesterol
Cat. No.：YN370706
| 产品名称: | 7-Dehydrocholesterol |
| CAS No.: | 434-16-2 |
| Chemical Name: | cholesta-5,7-dien-3β-ol |
| Synonyms: | 7-去氢胆固醇 |
| 分子量: | 384.64 |
| 分子式: | C₂₇H₄₄O |
| SMILES: | CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7-Dehydrocholesterol 是胆固醇和维生素 D3的生物合成前体。 |
| IC50和靶点: | |
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Xu, L., Liu, W., Sheflin, L.G., et al.Novel oxysterols observed in tissues and fluids of AY9944-treated rats: A model for Smith-Lemli-Opitz syndromeJ. Lipid Res.52,1810-1820(2011)
Xu, G., Salen, G., Shefer, S., et al.Reproducing abnormal cholesterol biosynthesis as seen in the Smith-Lemli-Opitz syndrome by inhibiting the conversion of 7-dehydrocholesterol to cholesterol in ratsJ. Clin. Invest.95(1),76-81(1995)
Lehmann, B., Genehr, T., Knuschke, P., et al.UVB-induced conversion of 7-dehydrocholesterol to 1α,25-dihydroxyvitamin D3 in an in vitro human skin equivalent modelJ. Invest. Dermatol.117(5),1179-1185(2001)
Chen, T.C., Chimeh, F., Lu, Z., et al.Factors that influence the cutaneous synthesis and dietary sources of vitamin DArch. Biochem. Biophys.460(2),213-217(2007)
