2-Methylcitric acid
Cat. No.:YN370738
CAS No. :6061-96-7
产品名称: | 2-Methylcitric acid |
CAS No.: | 6061-96-7 |
Chemical Name: | 2-hydroxy-1,2,3-butanetricarboxylic acid |
Synonyms: | Methylcitric acid |
分子量: | 206.15 |
分子式: | C₇H₁₀O₇ |
SMILES: | CC(C(O)=O)C(C(O)=O)(O)CC(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 2-Methylcitric acid (Methylcitric acid) 是 2- 甲基柠檬酸循环的内源性代谢物。2-Methylcitric acid 在甲基丙二酸血症和丙二酸酸血症中积累并能作为代谢标志物。2-Methylcitric acid 对谷氨酸支持的线粒体中 ADP 刺激和不耦合呼吸作用有明显的抑制作用。 |
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Allen, R.H., Stabler, S.P., Savage, D.G., et al.Elevation of 2-methylcitric acid I and II levels in serum, urine, and cerebrospinal fluid of patients with cobalamin deficiencyMetabolism42(8),978-988(1993)
Al-Dirbashi, O.Y., McIntosh, N., and Chakraborty, P.Quantification of 2-methylcitric acid in dried blood spots improves newborn screening for propionic and methylmalonic acidemiasJ. Med. Screen.24(2),58-61(2017)