3-Hydroxyisovaleric acid
Cat. No.：YN370750
CAS No. ：625-08-1
| 产品名称: | 3-Hydroxyisovaleric acid |
| CAS No.: | 625-08-1 |
| Chemical Name: | 3-hydroxy-3-methyl-butanoic acid |
| Synonyms: | β-羟基异戊酸,Beta-Hydroxyisovaleric acid |
| 分子量: | 118.13 |
| 分子式: | C₅H₁₀O₃ |
| SMILES: | CC(C)(O)CC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3-Hydroxyisovaleric acid 是尿液中排泄的正常内源性代谢产物 (endogenous metabolite)。3-Hydroxyisovaleric acid 的尿排泄是生物素缺乏的早期和敏感指标。 |
| IC50和靶点: | |
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Sabourin, P.J., and Bieber, L.L.Formation of β-hydroxyisovalerate by an α-ketoisocaproate oxygenase in human liverMetabolism32(2),160-164(1983)
Smith, H.J., Wyke, S.M., and Tisdale, M.J.Mechanism of the attenuation of proteolysis-inducing factor stimulated protein degradation in muscle by β-hydroxy-β-methylbutyrateCancer Res.64(23),8731-8735(2004)
Smith, H.J., Mukerji, P., and M.J., T.Attenuation of proteasome-induced proteolysis in skeletal muscle by β-hydroxy-β-methylbutyrate in cancer-induced muscle lossCancer Res.65(1),277-283(2005)
Yu, W.M., Kuhara, T., Inoue, Y., et al.Increased urinary excretion of β-hydroxyisovaleric acid in ketotic and non-ketotic type II diabetes mellitusClin. Chim. Acta188(2),161-168(1990)
