3-Methylglutaric acid
Cat. No.:YN370751
CAS No. :626-51-7
产品名称: | 3-Methylglutaric acid |
CAS No.: | 626-51-7 |
Chemical Name: | 3-methyl-pentanedioic acid |
Synonyms: | 3-甲基戊二酸 |
分子量: | 146.14 |
分子式: | C₆H₁₀O₄ |
SMILES: | O=C(O)CC(C)CC(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 3-Methylglutaric acid 是一种亮氨酸代谢物,是与两种亮氨酸途径 HMGCL、AUH 酶缺陷显著相关的 C6 二元羧酸有机酸。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Mack, M., Schniegler-Mattox, U., Peters, V., et al.Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolismFEBS J.273(9),2012-2022(2006)
Riberio, C.A.J., Hickmann, F.H., and Wajner, M.Neurochemical evidence that 3-methylglutaric acid inhibits synaptic Na+,K+-ATPase activity probably through oxidative damage in brain cortex of young ratsInt. J. Dev. Neurosci.29(1),1-7(2011)
Leipnitz, G., Seminotti, B., Amaral, A.U., et al.Induction of oxidative stress by the metabolites accumulating in 3-methylglutaconic aciduria in cerebral cortex of young ratsLife Sci.82(11-12),652-662(2008)