8-Dehydrocholesterol
Cat. No.：YN370759
CAS No. ：70741-38-7
| 产品名称: | 8-Dehydrocholesterol |
| CAS No.: | 70741-38-7 |
| Chemical Name: | cholesta-5,8-dien-3β-ol |
| Synonyms: | |
| 分子量: | 384.64 |
| 分子式: | C₂₇H₄₄O |
| SMILES: | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])C3=C([C@@]4(C(C[C@@H](O)CC4)=CC3)C)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 8-Dehydrocholesterol 水平的升高是诊断史密斯-莱姆利奥普茨综合征 (SLOS) 的生化特征之一。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Wolf, C., Chevy, F., Pham, J., et al.Changes in serum sterols of rats treated with 7-dehydrocholesterol-Δ7-reductase inhibitors: Comparison to levels in humans with Smith-Lemli-Opitz syndromeJ. Lipid. Res.37(6),1325-1333(1996)
Björkhem, I., Starck, L., Andersson, U., et al.Oxysterols in the circulation of patients with the Smith-Lemli-Opitz syndrome: Abnormal levels of 24S- and 27-hydroxycholesterolJ. Lipid Res.42(3),366-371(2001)
Griffiths, W.J., Abdel-Khalik, J., Crick, P.J., et al.Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patientsJ. Steroid Biochem. Mol. Biol.169,77-87(2017)
