Leukotriene C4
Cat. No.:YN370763
CAS No. :72025-60-6
产品名称: | Leukotriene C4 |
CAS No.: | 72025-60-6 |
Chemical Name: | 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
Synonyms: | |
分子量: | 625.77 |
分子式: | C₃₀H₄₇N₃O₉S |
SMILES: | OC(CCC[C@H](O)[C@@H](/C=C/C=C/C=C\C/C=C\CCCCC)SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets. Leukotriene C4 |
IC50和靶点: | |
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Maclouf, J.A., and Murphy, R.C.Transcellular metabolism of neutrophil-derived leukotriene A4 by human platelets. A potential cellular source of leukotriene C4J. Biol. Chem.263(1),174-181(1988)
Piper, P.J.Formation and actions of leukotrienesPhysiol. Rev.64(2),744-761(1984)
Samuelsson, B.Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammationScience220(4597),568-575(1983)
Lefer, A.M.Leukotrienes as mediators of ischemia and shockBiochem. Pharmacol.35(2),123-127(1986)