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11-Oxo etiocholanolone

Cat. No.:YN370767

  • CAS No. :739-27-5

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    • 参考文献
    • 产品名称: 11-Oxo etiocholanolone
      CAS No.: 739-27-5
      Chemical Name: (5β)-3α-hydroxy-androstane-11,17-dione
      Synonyms:11-Ketoetiocholanolone
      分子量:304.42
      分子式:C₁₉H₂₈O₃
      SMILES:C[C@@]([C@](C1)([H])CC2)(CC[C@H]1O)[C@](C(C3)=O)([H])[C@]2([H])[C@@](CCC4=O)([H])[C@]34C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 11-Oxo etiocholanolone (11-Ketoetiocholanolone) 是 Etiocholanolone 的代谢产物。Etiocholanolone 是睾丸激素的排泄代谢产物,具有抗惊厥活性。
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    • Schiffer, L., Barnard, L., Baranowski, E.S., et al.Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive reviewJ. Steroid Biochem. Mol. Biol.194,105439(2019)

      Barnard, L., Nikolaou, N., Louw, C., et al.The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1J. Steroid Biochem. Mol. Biol.202,105724(2020)

      Birke, G., Gemzell, C.A., Plantin, L.O., et al.Plasma levels of 17-hydroxycorticosteroids and urinary excretion pattern of keto-steroids in normal pregnancyActa Endocrinol. (Copenh.)27(4),389-402(1958)

      Jung, B.H., Bai, S.W., and Chung, B.C.Endogenous urinary steroids in premenopausal women with uterine leiomyomasInt. J. Gynaecol. Obstet.84(1),55-60(2004)

      Molina-García, L., Pérez, J.M., Sarasa, M., et al.HPLC-QTOF method for quantifying 11-ketoetiocholanolone, a cortisol metabolite, in ruminants' feces: Optimization and validationEcol. Evol.8(18),9218-9228(2018)

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