11-Oxo etiocholanolone
Cat. No.:YN370767
CAS No. :739-27-5
产品名称: | 11-Oxo etiocholanolone |
CAS No.: | 739-27-5 |
Chemical Name: | (5β)-3α-hydroxy-androstane-11,17-dione |
Synonyms: | 11-Ketoetiocholanolone |
分子量: | 304.42 |
分子式: | C₁₉H₂₈O₃ |
SMILES: | C[C@@]([C@](C1)([H])CC2)(CC[C@H]1O)[C@](C(C3)=O)([H])[C@]2([H])[C@@](CCC4=O)([H])[C@]34C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 11-Oxo etiocholanolone (11-Ketoetiocholanolone) 是 Etiocholanolone 的代谢产物。Etiocholanolone 是睾丸激素的排泄代谢产物,具有抗惊厥活性。 |
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Schiffer, L., Barnard, L., Baranowski, E.S., et al.Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive reviewJ. Steroid Biochem. Mol. Biol.194,105439(2019)
Barnard, L., Nikolaou, N., Louw, C., et al.The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1J. Steroid Biochem. Mol. Biol.202,105724(2020)
Birke, G., Gemzell, C.A., Plantin, L.O., et al.Plasma levels of 17-hydroxycorticosteroids and urinary excretion pattern of keto-steroids in normal pregnancyActa Endocrinol. (Copenh.)27(4),389-402(1958)
Jung, B.H., Bai, S.W., and Chung, B.C.Endogenous urinary steroids in premenopausal women with uterine leiomyomasInt. J. Gynaecol. Obstet.84(1),55-60(2004)
Molina-García, L., Pérez, J.M., Sarasa, M., et al.HPLC-QTOF method for quantifying 11-ketoetiocholanolone, a cortisol metabolite, in ruminants' feces: Optimization and validationEcol. Evol.8(18),9218-9228(2018)