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3-Carbamoyl-1-methylpyridin-1-ium chloride

Cat. No.:YN370781

  • CAS No. :1005-24-9

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    • 参考文献
    • 产品名称: 3-Carbamoyl-1-methylpyridin-1-ium chloride
      CAS No.: 1005-24-9
      Chemical Name: 3-(aminocarbonyl)-1-methyl-pyridinium, monochloride
      Synonyms:1-methylpyridin-1-ium-3-carboxamide hydrochloride,1-Methylnicotinamide chloride,3-Carbamoyl-1-methylpyridinium Chloride,3-氨基甲酰-1-甲基氯化吡啶,Nicotinamide Chloromethylate
      分子量:172.61
      分子式:C₇H₉ClN₂O
      SMILES:C[N+]1=CC=CC(C(N)=O)=C1.[Cl-]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 3-Carbamoyl-1-methylpyridin-1-ium chloride 是一种内源性代谢产物。
      IC50和靶点:
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    • Alston, T.A., and Abeles, R.H.Substrate specificity of nicotinamide methyltransferase isolated from porcine liverArch. Biochem. Biophys.260(2),601-608(1988)

      Chlopicki, S., Swies, J., Mogielnicki, A., et al.1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathwayBr. J. Pharmacol.152(2),230-239(2007)

      Domagala, T.B., Szeffler, A., Dobrucki, L.W., et al.Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vesselsHypertension59(4),825-832(2012)

      Ulanovskaya, O.A., Zuhl, A.M., and Cravatt, B.F.NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sinkNat. Chem. Biol.9(5),300-306(2013)

      Shlomi, T., and Rabinowitz, J.D.Cancer mistunes methylationNat. Chem. Biol.9(5),293-294(2013)

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