3-Carbamoyl-1-methylpyridin-1-ium chloride
Cat. No.:YN370781
CAS No. :1005-24-9
产品名称: | 3-Carbamoyl-1-methylpyridin-1-ium chloride |
CAS No.: | 1005-24-9 |
Chemical Name: | 3-(aminocarbonyl)-1-methyl-pyridinium, monochloride |
Synonyms: | 1-methylpyridin-1-ium-3-carboxamide hydrochloride,1-Methylnicotinamide chloride,3-Carbamoyl-1-methylpyridinium Chloride,3-氨基甲酰-1-甲基氯化吡啶,Nicotinamide Chloromethylate |
分子量: | 172.61 |
分子式: | C₇H₉ClN₂O |
SMILES: | C[N+]1=CC=CC(C(N)=O)=C1.[Cl-] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 3-Carbamoyl-1-methylpyridin-1-ium chloride 是一种内源性代谢产物。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Alston, T.A., and Abeles, R.H.Substrate specificity of nicotinamide methyltransferase isolated from porcine liverArch. Biochem. Biophys.260(2),601-608(1988)
Chlopicki, S., Swies, J., Mogielnicki, A., et al.1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathwayBr. J. Pharmacol.152(2),230-239(2007)
Domagala, T.B., Szeffler, A., Dobrucki, L.W., et al.Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vesselsHypertension59(4),825-832(2012)
Ulanovskaya, O.A., Zuhl, A.M., and Cravatt, B.F.NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sinkNat. Chem. Biol.9(5),300-306(2013)
Shlomi, T., and Rabinowitz, J.D.Cancer mistunes methylationNat. Chem. Biol.9(5),293-294(2013)