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Acetyl Coenzyme A trisodium

Cat. No.:YN370782

  • CAS No. :102029-73-2

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    • 参考文献
    • 产品名称: Acetyl Coenzyme A trisodium
      CAS No.: 102029-73-2
      Chemical Name: S-acetate coenzyme A, trisodium salt
      Synonyms:Acetyl-CoA trisodium
      分子量:875.52
      分子式:C₂₃H₃₅N₇Na₃O₁₇P₃S
      SMILES:O[C@H]1[C@@H](O[C@H](COP(OP(OCC(C)([C@@H](O)C(NCCC(NCCSC(C)=O)=O)=O)C)(O[Na])=O)(O)=O)[C@H]1OP(O[Na])(O[Na])=O)N2C3=C(C(N)=NC=N3)N=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) 是一种重要的代谢中间产物。Acetyl Coenzyme A trisodium 是糖酵解丙酮酸进入三羧酸 (TCA) 循环的实际分子,是脂质合成的关键前体,并且是乙酰基乙酰化的唯一供体,还是一种丙酮酸羧化酶 (PC) 的有效变构活化剂。
      IC50和靶点:
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    • Akram, M.Citric acid cycle and role of its intermediates in metabolismCell Biochem. Biophys.68(3),475-478(2014)

      Salminen, A., Kauppinen, A., Hiltunen, M., et al.Krebs cycle intermediates regulate DNA and histone methylation: Epigenetic impact on the aging processAgeing Res. Rev.16C,45-65(2014)

      Zaidi, N., Swinnen, J.V., and Smans, K.ATP-citrate lyase: A key player in cancer metabolismCancer Res.72(15),3709-3714(2012)

      Palsson-McDermott, E.M., and O'Neill, L.A.The Warburg effect then and now: From cancer to inflammatory diseasesBioEssays35(11),965-973(2013)

      Miura, Y.The biological significance of ω-oxidation of fatty acidsProc. Jpn. Acad. Ser. B Phys. Biol. Sci.89(8),370-382(2013)

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