Resolvin E1
Cat. No.：YN370786
CAS No. ：552830-51-0
| 产品名称: | Resolvin E1 |
| CAS No.: | 552830-51-0 |
| Chemical Name: | 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid |
| Synonyms: | RvE1 |
| 分子量: | 350.45 |
| 分子式: | C₂₀H₃₀O₅ |
| SMILES: | CC[C@@H](O)/C=C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Resolvin E1 (RvE1) 是一种有效的促炎症反应介质，衍生自 omega-3 脂肪酸二十碳五烯酸 (EPA)。Resolvin E1 是在急性炎症的自发消退阶段 (存在特定的细胞间相互作用) 中，在阿司匹林存在下从 EPA 内源性生物合成的。Resolvin E1 具有独特的反调节作用，可以抑制多形核白细胞 (PMN) 跨内皮迁移。Resolvin E1 还可作为白细胞浸润，树突状细胞迁移和 IL-12 产生的有效抑制剂。 |
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Oh, S.F., Pillai, P.S., Recchiuti, A., et al.Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammationJ. Clin. Invest.121(2),569-581(2011)
Arita, M., Yoshida, M., Hong, S., et al.Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitisProc. Natl. Acad. Sci. USA102(21),7671-7676(2005)
Aoki, H., Hisada, T., Ishizuka, T., et al.Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthmaBiochem. Biophys. Res. Commun.367(2),509-515(2008)
