11-Beta-hydroxyandrostenedione
Cat. No.：YN370817
| 产品名称: | 11-Beta-hydroxyandrostenedione |
| CAS No.: | 382-44-5 |
| Chemical Name: | (11β)-11-hydroxy-androst-4-ene-3,17-dione |
| Synonyms: | 4-Androsten-11β-ol-3,17-dione |
| 分子量: | 302.41 |
| 分子式: | C₁₉H₂₆O₃ |
| SMILES: | C[C@]12CCC(C=C1CC[C@@]([C@]2([H])[C@@H](O)C[C@@]34C)([H])[C@]3([H])CCC4=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) 是一种主要存在于肾上腺的类固醇 (11β-羟化酶存在于肾上腺组织，但在卵巢组织中不存在)。11-Beta-hydroxyandrostenedione 是一种 11β-羟基类固醇脱氢酶 (11βHSD) 同工酶抑制剂。随着 4-androstenedione 的增加，测量血浆 11-Beta-hydroxyandrostenedione 可以区分高雄激素血症的肾上腺或卵巢起源。 |
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Storbeck, K.-H., Bloem, L.M., Africander, D., et al.11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: A putative role in castration resistant prostate cancer?Mol. Cell. Endocrinol.377(1-2),135-146(2013)
