α-Muricholic acid
Cat. No.:YN370827
CAS No. :2393-58-0
产品名称: | α-Muricholic acid |
CAS No.: | 2393-58-0 |
Chemical Name: | (3α,5β,6β,7α)-3,6,7-trihydroxy-cholan-24-oic acid |
Synonyms: | |
分子量: | 408.57 |
分子式: | C₂₄H₄₀O₅ |
SMILES: | C[C@@]([C@]1([H])[C@H](O)[C@H]2O)(CC[C@@H](O)C1)[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(O)=O)([H])[C@]4(C)CC3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | α-Muricholic acid 是一种啮齿动物中含量最丰富的伯胆汁酸。 |
IC50和靶点: | |
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Eyssen, H.J., Parmentier, G.G., and Mertens, J.A.Sulfate bile acids in germ-free and conventional miceEur. J. Biochem.66(3),507-514(1976)
Uehara, T., Xi Peng, X., Bennett, B., et al.c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantationTransplantation78(3),324-332(2004)
Watanabe, K., Igarashi, M., Li, X., et al.Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acidsPLoS One13(8),e0202083(2018)
La Frano, M.R., Hernandez-Carretero, A., Weber, N., et al.Diet-induced obesity and weight loss alter bile acid concentrations and bile acid-sensitive gene expression in insulin target tissues of C57BL/6J miceNutr. Res.46,11-21(2017)