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(±)20-HDHA

Cat. No.:YN370846

  • CAS No. :90906-41-5

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    • 生物活性
    • 参考文献
    • 产品名称: (±)20-HDHA
      CAS No.: 90906-41-5
      Chemical Name: (±)20-hydroxy-4Z,7Z,10Z,13Z,16Z,18E-docosahexaenoic acid
      Synonyms:(±)20-HDoHE
      分子量:344.49
      分子式:C₂₂H₃₂O₃
      SMILES:CCC(O)/C=C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (±)20-HDHA ((±)20-HDoHE) 是一种外消旋混合物,是一种二十二碳六烯酸 (DHA) 的自氧化产物。(±)20-HDHA 也可以通过人血小板和大鼠脑匀浆中的过氧化过程形成。
      IC50和靶点:
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    • VanRollins, M., and Murphy, R.C.Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoateJ. Lipid Res.25(5),507-517(1984)

      Reynaud, D., Thickitt, C.P., and Pace-Asciak, C.R.Facile preparation and structural determination of monohydroxy derivatives of docosahexaenoic acid (HDoHE) by α-tocopherol-directed autoxidationAnal. Biochem.214(1),165-170(1993)

      VanRollins, M., Baker, R.C., Sprecher, H., et al.Oxidation of docosahexaenoic acid by rat liver microsomesJ. Biol. Chem.259(9),5776-5783(1984)

      Yamane, M., Abe, A., and Yamane, S.High-performance liquid chromatography-thermospray mass spectrometry of epoxy polyunsaturated fatty acids and epoxyhydroxy polyunsaturated fatty acids from an incubation mixture of rat tissue homogenateJ. Chromatogr.652(2),123-136(1994)

      Kim, H.Y., Karanian, J.W., Shingu, T., et al.Sterochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenateProstaglandins40(5),473-490(1990)

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