Hydroxy bosentan
Cat. No.：YN370922
CAS No. ：253688-60-7
| 产品名称: | Hydroxy bosentan |
| CAS No.: | 253688-60-7 |
| Chemical Name: | 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide |
| Synonyms: | Ro 48-5033 |
| 分子量: | 567.61 |
| 分子式: | C₂₇H₂₉N₅O₇S |
| SMILES: | COC1=CC=CC=C1OC2=C(N=C(N=C2OCCO)C3=NC=CC=N3)NS(C4=CC=C(C=C4)C(CO)(C)C)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hydroxy bosentan (Ro 48-5033) 是 Bosentan (BOS) 被肝脏中的细胞色素 P450 系统代谢的后的主要代谢产物。Ro 48-5033 在药理上协助 BOS，保留 10％-20％ 的活性。 |
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Dingemanse, J., and van Giergsbergen, L.M.Clinical pharmacology of bosentan, a dual endothelin receptor antagonistClin. Pharmacokinet.43(15),1089-1115(2004)
