20(S)-Hydroxycholesterol
Cat. No.：YN370969
CAS No. ：516-72-3
| 产品名称: | 20(S)-Hydroxycholesterol |
| CAS No.: | 516-72-3 |
| Chemical Name: | cholest-5-ene-3β,20-diol |
| Synonyms: | 20α-Hydroxycholesterol |
| 分子量: | 402.65 |
| 分子式: | C₂₇H₄₆O₂ |
| SMILES: | C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) 是平滑(smo)癌蛋白的变构激活剂，在以 NIH3T3 细胞的基因转录报告实验中，激活 hedgehog (Hh) 信号通路的EC50值为 3 μM。 |
| IC50和靶点: | |
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Kim, W.-K., Meliton, V., Tetradis, S., et al.Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cellsJ. Bone Miner. Metab.25(4),782-795(2010)
