SAICAR
Cat. No.：YN371071
CAS No. ：3031-95-6
| 产品名称: | SAICAR |
| CAS No.: | 3031-95-6 |
| Chemical Name: | N-[[5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazol-4-yl]carbonyl]-L-aspartic Acid; N-[(5-Amino-1-β-D-ribofuranosylimidazol-4-yl)carbonyl]- |
| Synonyms: | |
| 分子量: | 454.28 |
| 分子式: | C₁₃H₁₉N₄O₁₂P |
| SMILES: | O=C(O)C[C@@H](C(O)=O)NC(C1=C(N)N([C@H]2[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O2)O)O)C=N1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SAICAR 是嘌呤核苷酸从头合成的中间体，以同工酶选择性性方式激活PKM2，EC50为 0.3 mM。SAICAR 刺激 PKM2 并促进癌细胞在葡萄糖限制条件下的存活。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Gollub, E.G., et al.: J. Bacteriol., 78,В 320 (1959), Srivastava, P.C., et al.: J. Med. Chem.,В 17, 1207 (1974),
