12-Ketodeoxycholic acid
Cat. No.：YN371613
CAS No. ：5130-29-0
| 产品名称: | 12-Ketodeoxycholic acid |
| CAS No.: | 5130-29-0 |
| Chemical Name: | (3α,5β)-3-hydroxy-12-oxo-cholan-24-oic acid |
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| 分子量: | 390.56 |
| 分子式: | C₂₄H₃₈O₄ |
| SMILES: | C[C@H](CCC(O)=O)[C@H]([C@]12C)CC[C@@]1([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 12-Ketodeoxycholic acid 是一种胆汁酸，是肾脏的代谢物。12-Ketodeoxycholic acid 可以作为肾脏损伤的标志物。 |
| IC50和靶点: | |
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Franco, P., Porru, E., Fiori, J., et al.Identification and quantification of oxo-bile acids in human faeces with liquid chromatography-mass spectrometry: A potent tool for human gut acidic sterolbiome studiesJ. Chromatogr. A.1585,70-81(2019)
Sakai, K., Makino, T., Kawai, Y., et al.Intestinal microflora and bile acids. Effect of bile acids on the distribution of microflora and bile acid in the digestive tract of the ratMicrobiol. Immunol.24(3),187-196(1980)
Krasowski, M.D., Yasuda, K., Hagey, L.R., et al.Evolution of the pregnane X receptor: Adaptation to cross-species differences in biliary bile saltsMol. Endocrinol.19(7),1720-1739(2005)
Andersén, E., Karlaganis, G., and Sjövall, J.Altered bile acid profiles in duodenal bile and urine in diabetic subjectsEur. J. Clin. Invest.18(2),166-172(1988)
