Folinic acid calcium
Cat. No.：YN371761
| 产品名称: | Folinic acid calcium |
| CAS No.: | 1492-18-8 |
| Chemical Name: | N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, monocalcium salt |
| Synonyms: | 亚叶酸钙; Leucovorin calcium; Calcium folinate |
| 分子量: | 511.50 |
| 分子式: | C₂₀H₂₁CaN₇O₇ |
| SMILES: | O=C(N[C@H](C([O-])=O)CCC([O-])=O)C(C=C1)=CC=C1NCC(N2C=O)CNC3=C2C(N=C(N)N3)=O.[Ca+2] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Folinic acid calcium (Leucovorin calcium) 是一种生物叶酸，通常与甲氨蝶呤 (MTX) 一起作为挽救剂服用，以降低 MTX 诱导的毒性。 |
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Danenberg, P.V., Gustavsson, B., Johnston, P., et al.Folates as adjuvants to anticancer agents: Chemical rationale and mechanism of actionCrit. Rev. Oncol. Hematol.106,118-131(2016)
Frye, R.E., Rossignol, D., Casanova, M.F., et al.A review of traditional and novel treatments for seizures in autism spectrum disorder: Findings from a systematic review and expert panelFront. Public Health1,31(2013)
