sn-Glycero-3-phosphocholine
Cat. No.：YN372455
| 产品名称: | sn-Glycero-3-phosphocholine |
| CAS No.: | 28319-77-9 |
| Chemical Name: | 2-[[[(2R)-2,3-dihydroxypropoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt |
| Synonyms: | 甘磷酸胆碱; Choline Alfoscerate; Alpha-GPC; L-α-GPC |
| 分子量: | 257.22 |
| 分子式: | C₈H₂₀NO₆P |
| SMILES: | O=P(OCC[N+](C)(C)C)(OC[C@H](O)CO)[O-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | sn-Glycero-3-phosphocholine (Choline Alfoscerate) 是脑磷脂生物合成的前体，可提高胆碱在神经组织中的生物利用度。sn-Glycero-3-phosphocholine (Choline Alfoscerate) 对认知功能有显著影响，具有良好的安全性和耐受性，可用于阿尔茨海默病和痴呆症的研究。 |
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Traini, E., Bramanti, V., and Amenta, F.Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipid with a still interesting profile as cognition enhancing agent.Curr. Alzheimer Res.10(10),1070-1079(2013)
Sigala, S., Imperato, A., Rizzonelli, P., et al.L-α-glycerylphosphorylcholine antagonizes scopolamine-induced amnesia and enhances hippocampal cholinergic transmission in the ratEur. J. Pharmacol.211(3),351-358(1992)
