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L-Thyroxine

Cat. No.:YN372482

  • CAS No. :51-48-9

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: L-Thyroxine
      CAS No.: 51-48-9
      Chemical Name: O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
      Synonyms:Levothyroxine; T4
      分子量:776.87
      分子式:C₁₅H₁₁I₄NO₄
      SMILES:N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: L-Thyroxine (Levothyroxine; T4) 是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。DIO 酶将 L-Thyroxine (T4) 转化成具有生物活性的三碘甲状腺氨酸 (T3)。
      IC50和靶点:
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    • Bowers, C.Y., Schally, A.V., Reynolds, G.A., et al.Interactions of L-thyroxine or L-triiodothyronine and thyrotropin-releasing factor on the release and synthesis of thyrotropin from the anterior pituitary gland of miceEndocrinology81(4),741-747(1967)

      Fabris, N., Muzzioli, M., and Mocchegiani, E.Recovery of age-dependent immunological deterioration in Balb/c mice by short-term treatment with L-thyroxineMech. Ageing Dev.18(4),327-338(1982)

      Fabris, N., and Mocchegiani, E.Endocrine control of thymic serum factor production in young-adult and old miceCell Immunol.91(2),325-335(1985)

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