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3-Methylxanthine

Cat. No.:YN372641

  • CAS No. :1076-22-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 3-Methylxanthine
      CAS No.: 1076-22-8
      Chemical Name: 3,9-dihydro-3-methyl-1H-purine-2,6-dione
      Synonyms:3-MX
      分子量:166.14
      分子式:C₆H₆N₄O₂
      SMILES:O=C1N(C)C2=C(N=CN2)C(N1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 3-Methylxanthine 是黄嘌呤衍生物,能够抑制GMP,在豚鼠分离的气管肌肉中测得其IC50值为 920 μM。
      IC50和靶点: [{name:"GMP:920 μM (IC50)'}, 'Human Endogenous Metabolite']
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Tanaka, H., Ogawa, K., Takagi, K., et al.Inhibition of cyclic GMP phosphodiesterase by xanthine derivatives relaxes guinea-pig trachealis smooth muscleClin. Exp. Pharmacol. Physiol.18(3),163-168(1991)

      Camandola, S., Plick, N., and Mattson, M.P.Impact of coffee and cacao purine metabolites on neuroplasticity and neurodegenerative diseaseNeurochem. Res.44(1),214-227(2019)

      Ha, H.R., Chen, J., Freiburghaus, A.U., et al.Metabolism of theophylline by cDNA-expressed human cytochromes P-450Br. J. Clin. Pharmacol.39(3),321-326(1995)

      Yamamoto, K., Toyama, E., Kawakami, J., et al.Neurotoxic convulsions induced by theophylline and its metabolites in miceBiol. Pharm. Bull.19(6),869-872(1996)

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