Dihomo-γ-linolenic acid
Cat. No.：YN372714
CAS No. ：1783-84-2
| 产品名称: | Dihomo-γ-linolenic acid |
| CAS No.: | 1783-84-2 |
| Chemical Name: | 8Z,11Z,14Z-eicosatrienoic acid |
| Synonyms: | all-cis-8,11,14-Eicosatrienoic acid |
| 分子量: | 306.48 |
| 分子式: | C₂₀H₃₄O₂ |
| SMILES: | CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) 是 20 个碳的 ω-6 脂肪酸，具有抗炎和抗增殖活性。Dihomo-γ-linolenic acid 能减弱载脂蛋白 E 缺陷小鼠模型模型的动脉粥样硬化。 |
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Bell, J.G., Tocher, D.R., and Sargent, J.R.Effect of supplementation with 20:3(n-3), 20:4(n-6) and 20:5(n-3) on the production of prostaglandins E and F of the 1-, 2- and 3-series in turbot (Scophthalmus maximus) brain astroglial cells in primary cultureBiochim. Biophys. Acta1211,335-342(1994)
Levin, G., Duffin, K.L., Obukowicz, M.G., et al.Differential metabolism of dihomo-γ-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: Implications for cellular synthesis of prostaglandin E1 and prostaglandin E2Biochem. J.365(Pt 2),489-496(2002)
Kawashima, H., Tateishi, N., Shiraishi, A., et al.Oral administration of dihomo-γ-linolenic acid prevents development of atopic dermatitis in NC/Nga miceLipids43(1),37-43(2007)
Takai, S., Jin, D., Kawashima, H., et al.Anti-atherosclerotic effects of dihomo-γ-linolenic acid in ApoE-deficient miceJ. Atheroscler. Thromb.16(4),480-489(2009)
