Docetaxel
Cat. No.：YN372719
CAS No. ：114977-28-5
| 产品名称: | Docetaxel |
| CAS No.: | 114977-28-5 |
| Chemical Name: | |
| Synonyms: | 多西他赛; RP-56976 |
| 分子量: | 807.88 |
| 分子式: | C₄₃H₅₃NO₁₄ |
| SMILES: | O=C(OC(C)(C)C)N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@@H]2C(C)=C([C@@H](O)C([C@@]3(C)[C@]([C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]3O)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Docetaxel (RP-56976) 是一种微管解聚 (microtubule depolymerization) 抑制剂，其IC50值为 0.2 μM。Docetaxel 是紫杉醇的半合成类似物，能减弱 bcl-2 和 bcl-xL 基因表达的影响。Docetaxel 阻滞 G2/M 细胞周期，导致细胞凋亡 (apoptosis)。Docetaxel 具有抗肿瘤活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
