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17-Hydroxyprogesterone

Cat. No.:YN372866

  • CAS No. :68-96-2

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    • 生物活性
    • 参考文献
    • 产品名称: 17-Hydroxyprogesterone
      CAS No.: 68-96-2
      Chemical Name: 17-hydroxy-pregn-4-ene-3,20-dione
      Synonyms:17α-羟孕酮; 17α-Hydroxyprogesterone; 17-OHP
      分子量:330.46
      分子式:C₂₁H₃₀O₃
      SMILES:CC([C@@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 17-Hydroxyprogesterone (17-OHP)是一种内源性孕激素,在其他类固醇激素(包括糖皮质激素,雄激素,和雌激素)的生物合成中作为化学中间体。
      IC50和靶点:
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    • Mooij, C.F., Parajes, S., Pijnenburg-Kleizen, K.J., et al.Influence of 17-hydroxyprogesterone, progesterone and sex steroids on mineralocorticoid receptor transactivation in congenital adrenal hyperplasiaHorm. Res. Paediatr.83(6),414-421(2015)

      Pijnenburg-Kleizen, K.J., Engels, M., Mooij, C.F., et al.Adrenal steroid metabolites accumulating in congenital adrenal hyperplasia lead to transactivation of the glucocorticoid receptorEndocrinology156(10),3504-3510(2015)

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