Cotinine
Cat. No.：YN372888
CAS No. ：486-56-6
| 产品名称: | Cotinine |
| CAS No.: | 486-56-6 |
| Chemical Name: | 1-methyl-5S-(3-pyridinyl)-2-pyrrolidinone |
| Synonyms: | 可替宁; (-) |
| 分子量: | 176.22 |
| 分子式: | C₁₀H₁₂N₂O |
| SMILES: | O=C1N(C)[C@H](C2=CC=CN=C2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cotinine是烟草中的一种生物碱, 也是尼古丁的主要代谢物, 用作测量烟草烟雾成分的生物指标。 |
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Clemens, K.J., Caillé, S., Stinus, L., et al.The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in ratsInt. J. Neuropsychopharmacol.12(10),1355-1366(2009)
Terry, A.V., Jr., Hernandez, C.M., Hohnadel, E.J., et al.Cotinine, a neuroactive metabolite of nicotine: Potential for treating disorders of impaired cognitionCNS Drug Rev.11(3),229-252(2005)
Jacob, P., III, Yu, L., Shulgin, A.T., et al.Minor tobacco alkaloids as biomarkers for tobacco use: Comparison of users of cigarettes, smokeless tobacco, cigars, and pipesAm. J. Public Health89(5),731-736(1999)
Murphy, S.E., Link, C.A., Jensen, J., et al.A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokersCancer Epidemiol. Biomarkers Prev.13(10),1617-1623(2004)
