Pyridoxylamine dihydrochloride
Cat. No.：YN372942
| 产品名称: | Pyridoxylamine dihydrochloride |
| CAS No.: | 524-36-7 |
| Chemical Name: | 4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol, dihydrochloride |
| Synonyms: | 盐酸吡多胺,Pyridoxamine dihydrochloride,Pyridorin |
| 分子量: | 241.11 |
| 分子式: | C₈H₁₄Cl₂N₂O₂ |
| SMILES: | OCC1=C(CN)C(O)=C(C)N=C1.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyridoxylamine dihydrochloride 是糖基化终产物(AGE)和脂质化终产物(ALE)抑制剂，可防止糖尿病引起的视网膜血管病变。 |
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Kohlmeier, M.Water-soluble vitamins and nonnutrientsNutrient metabolism,567-671(2015)
Davies, S.S., Brantley, E.J., Voziyan, P.A., et al.Pyridoxamine analogues scavenge lipid-derived γ-ketoaldehydes and protect against H2O2-mediated cytotoxicityBiochemistry45(51),(2006)
Stitt, A., Gardiner, T.A., Alderson, N.L., et al.The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetesDiabetes51(9),2826-2832(2002)
Kassab, S., Begley, P., Church, S.J., et al.Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigationMol. Metab.28,107-119(2019)
