β-Nicotinamide mononucleotide
Cat. No.：YN372995
| 产品名称: | β-Nicotinamide mononucleotide |
| CAS No.: | 1094-61-7 |
| Chemical Name: | 3-(aminocarbonyl)-1-(5-O-phosphono-β-D-ribofuranosyl)-pyridinium, inner salt |
| Synonyms: | 烟酰胺单核苷酸; β-NM; NMN |
| 分子量: | 334.22 |
| 分子式: | C₁₁H₁₅N₂O₈P |
| SMILES: | NC(C1=C[N+]([C@@H]2O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]2O)=CC=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | β-nicotinamide mononucleotide (β-NM) 是烟酰胺磷酸核糖转移酶 (NAMPT) 反应的产物，NAD(+) 的关键中间体。β-nicotinamide mononucleotide 的作用包括其在细胞生化功能、心脏保护、糖尿病、阿尔茨海默病和肥胖相关并发症中的作用。 |
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Gallí, M., Van Gool, F., Rongvaux, A., et al.The nicotinamide phosphoribosyltransferase: A molecular link between metabolism, inflammation, and cancerCancer Res.70(1),8-11(2010)
Revollo, J.R., Körner, A., Mills, K.F., et al.Nampt/PBEF/visfatin regulates insulin secretion in Β cells as a systemic NAD biosynthetic enzymeCell Metab.6(5),363-375(2007)
Yoshino, J., Mills, K.F., Yoon, M.J., et al.Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in miceCell Metab.14(4),528-536(2011)
