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> 产品中心 > 抑制剂 & 激动剂 > Metabolic Enzyme/Protease > Endogenous Metabolite

Bilobalide

Cat. No.:YN373035

  • CAS No. :33570-04-6

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Bilobalide
      CAS No.: 33570-04-6
      Chemical Name: (3aS,5aR,8aS)-9R-(1,1-dimethylethyl)-10,10aS-dihydro-8R,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione
      Synonyms:白果内酯; (-)
      分子量:326.30
      分子式:C₁₅H₁₈O₈
      SMILES:O=C(O1)C[C@@]2([C@]1([H])C[C@]3(C(C)(C)C)O)[C@@]34[C@](OC([C@@H]4O)=O)([H])OC2=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Bilobalide是存在于银杏中的生物活性物,具有神经保护活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Defeudis, F.V.Bilobalide and neuroprotectionPharmacol. Res.46(6),565-568(2002)

      Kiewert, C., Kumar, V., Hildmann, O., et al.Role of glycine receptors and glycine release for the neuroprotective activity of bilobalideBrain Res.1201,143-150(2008)

      Lang, D., Kiewert, C., Mdzinarishvili, A., et al.Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivoBrain Res.1425,155-163(2011)

      Lau, A.J., Yang, G., Rajaraman, G., et al.Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptorDrug Metab. Dispos.40(1),178-186(2012)

      Deng, Y., Bi, H.C., Zhao, L.Z., et al.Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in ratsXenobiotica38(5),465-481(2008)

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