Bilobalide
Cat. No.:YN373035
CAS No. :33570-04-6
产品名称: | Bilobalide |
CAS No.: | 33570-04-6 |
Chemical Name: | (3aS,5aR,8aS)-9R-(1,1-dimethylethyl)-10,10aS-dihydro-8R,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione |
Synonyms: | 白果内酯; (-) |
分子量: | 326.30 |
分子式: | C₁₅H₁₈O₈ |
SMILES: | O=C(O1)C[C@@]2([C@]1([H])C[C@]3(C(C)(C)C)O)[C@@]34[C@](OC([C@@H]4O)=O)([H])OC2=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Bilobalide是存在于银杏中的生物活性物,具有神经保护活性。 |
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Defeudis, F.V.Bilobalide and neuroprotectionPharmacol. Res.46(6),565-568(2002)
Kiewert, C., Kumar, V., Hildmann, O., et al.Role of glycine receptors and glycine release for the neuroprotective activity of bilobalideBrain Res.1201,143-150(2008)
Lang, D., Kiewert, C., Mdzinarishvili, A., et al.Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivoBrain Res.1425,155-163(2011)
Lau, A.J., Yang, G., Rajaraman, G., et al.Species-dependent and receptor-selective action of bilobalide on the function of constitutive androstane receptor and pregnane X receptorDrug Metab. Dispos.40(1),178-186(2012)
Deng, Y., Bi, H.C., Zhao, L.Z., et al.Induction of cytochrome P450s by terpene trilactones and flavonoids of the Ginkgo biloba extract EGb 761 in ratsXenobiotica38(5),465-481(2008)