Luteolin
Cat. No.:YN373062
CAS No. :491-70-3
产品名称: | Luteolin |
CAS No.: | 491-70-3 |
Chemical Name: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
Synonyms: | 木犀草素; |
分子量: | 286.24 |
分子式: | C₁₅H₁₀O₆ |
SMILES: | O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C13 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Luteolin (Luteoline), 一种黄酮类化合物,也是一种有效的Nrf2抑制剂。Luteolin 具有抗炎和抗癌特性,可在人类多种癌细胞系 (包括非小肺癌细胞) 中诱导细胞凋亡和细胞周期停滞,并抑制细胞转移和血管生成。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Ueda, H., Yamazaki, C., and Yamazaki, M.Luteolin as an anti-inflammatory and anti-allergic constituent of Perilla frutescensBiol. Pharm. Bull.25(9),1197-1202(2002)
Sadik, C.D., Sies, H., and Schewe, T.Inhibition of 15-lipoxygenases by flavonoids: Structure-activity relations and mode of actionBiochem. Pharmacol.65(5),773-781(2003)
Sartor, L., Pezzato, E., Dell'Aica, I., et al.Inhibition of matrix-proteases by polyphenols: Chemical insights for anti-inflammatory and anti-invasion drug designBiochem. Pharmacol.64(2),229-237(2002)