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> 产品中心 > 抑制剂 & 激动剂 > Metabolic Enzyme/Protease > Endogenous Metabolite

3-​Oxocholic acid

Cat. No.:YN373406

  • CAS No. :2304-89-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 3-​Oxocholic acid
      CAS No.: 2304-89-4
      Chemical Name: (5β,7α,12α)-7,12-dihydroxy-3-oxo-cholan-24-oic acid
      Synonyms:
      分子量:406.56
      分子式:C₂₄H₃₈O₅
      SMILES:C[C@H](CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])CC(CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: 3-Oxocholic acid 是一种氧胆汁酸的代谢产物,也是产气荚膜梭菌在肠道中由胆汁产生的主要降解产物。3-Oxocholic acid 是一种类固醇酸,主要存在于哺乳动物的胆汁中。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Wahlström, A., Sayin, S.I., Marschall, H.-I., et al.Intestinal crosstalk between bile acids and microbiota and its impact on host metabolismCell Metab.24(1),41-50(2016)

      Macdonald, I.A., Forrest, T.P., Costain, G.A., et al.Identification of 7α-, 12α-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringensJ. Steroid Biochem.9(4),353-358(1978)

      Yan, K., Chen, W., Zhu, H., et al.The changes of serum metabolites in diabetic GK rats after ileal transposition surgeryObes. Surg.29(3),882-890(2019)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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