Protirelin
Cat. No.：YN373430
| 产品名称: | Protirelin |
| CAS No.: | 24305-27-9 |
| Chemical Name: | 5-oxo-L-prolyl-L-histidyl-L-prolinamide |
| Synonyms: | 普罗瑞林; Synthetic thyrotropin-releasing factor; Synthetic thyrotropin-releasing hormone; TRF; TRH; TSH-RF; pGlu-His-Pro-NH2; {pGLU}HP-NH2 |
| 分子量: | 362.38 |
| 分子式: | C₁₆H₂₂N₆O₄ |
| SMILES: | O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC3)NC3=O)=O)=O)CCC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Protirelin 是一种高度保守的神经肽，发挥促甲状腺激素 (TSH) 水平的激素控制作用，及神经调节功能。 |
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Dettmar, P.W., Lynn, A.G., Metcalf, G., et al.The ability of RX 77368 - a stabilised analogue of TRH - to provoke the secretion of prolactin and TSH in vivoNeuropeptides3(1),1-8(1982)
Yamada, M., Iwasaki, T., Satoh, T., et al.Activation of the thyrotropin-releasing hormone (TRH) receptor by a direct precursor of TRH, TRH-GlyNeurosci. Lett.196(1-2),109-112(1995)
Bhargava, H.N., and Das, S.Evidence for opiate action at the brain receptors for thyrotropin-releasing hormoneBrain Res.368(2),262-267(1986)
Martin, T.F.J.Thyrotropin-releasing hormone rapidly activates the phosphodiester hydrolysis of polyphosphoinositides in GH3 pituitary cells. Evidence for the role of a polyphosphoinositide-specific phospholipase C in hormone actionJ. Biol. Chem.258(24),14816-14822(1983)
Iriuchijima, T., Michimata, T., Miyashita, K., et al.Thyroid hormones regulate the formation of inositol phosphate in response to thyrotropin-releasing hormone in rat anterior pituitariesNeuropeptides21(1),49-53(1992)
Apfelbaum, M.E.Role of vasoactive intestinal peptide and 5-HT2 receptor subtype in serotonin stimulation of basal and thyrotropin-releasing-hormone-induced prolactin release in vitro from rat pituitary cellsNeuroendocrinology67(1),45-50(1998)
