5-Hydroxymethyluracil
Cat. No.：YN374040
CAS No. ：4433-40-3
| 产品名称: | 5-Hydroxymethyluracil |
| CAS No.: | 4433-40-3 |
| Chemical Name: | 5-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione |
| Synonyms: | a-Hydroxythymine,5-羟甲基脲嘧啶,Hydroxymethyl Uracil,5-(Hydroxymethyl)uracil |
| 分子量: | 142.11 |
| 分子式: | C₅H₆N₂O₃ |
| SMILES: | O=C1NC(C(CO)=CN1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 5-Hydroxymethyluracil 是氧化性 DNA 损伤的产物。5-Hydroxymethyluracil 可用作增强或抑制细菌 RNA 聚合酶转录的潜在表观遗传标记。 |
| IC50和靶点: | |
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Zastawny, T.H., Altman, S.A., Randers-Eichhorn, L., et al.DNA base modifications and membrane damage in cultured mammalian cells treated with iron ionsFree Radic. Biol. Med.18,1013-1022(1995)
Spencer, J.P.E., Jenner, A., Chimel, K., et al.DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cellsFEBS Lett.374(2),233-236(1995)
Jaruga, P., Zastawny, T.H., Skokowski, J., et al.Oxidative DNA base damage and antioxidant enzyme activities in human lung cancerFEBS Lett.341,59-64(1994)
