5a-Pregnane-3,20-dione
Cat. No.：YN374048
CAS No. ：566-65-4
| 产品名称: | 5a-Pregnane-3,20-dione |
| CAS No.: | 566-65-4 |
| Chemical Name: | (5α)-pregnane-3,20-dione |
| Synonyms: | 伊格列净脯氨酸, L-脯氨酸伊格列净 |
| 分子量: | 316.48 |
| 分子式: | C₂₁H₃₂O₂ |
| SMILES: | CC([C@H]1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 5a-Pregnane-3,20-dione 是一种内源性的孕酮代谢物。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Scholtz, E.L., Krishnan, S., Ball, B.A., et al.Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesteroneProc. Natl. Acad. Sci. USA111(9),3365-3370(2014)
Guennoun, R., Labombarda, F., Gonzalez Deniselle, M.C., et al.Progesterone and allopregnanolone in the central nervous system: Response to injury and implication for neuroprotectionJ. Steroid Biochem. Mol. Biol.146,48-61(2015)
Wiebe, J.P., Rivas, M.A., Mercogliano, M.F., et al.Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasterideJ. Steroid Biochem. Mol. Biol.149,27-34(2015)
