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1-Methylxanthine

Cat. No.:YN374076

  • CAS No. :6136-37-4

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    • 参考文献
    • 产品名称: 1-Methylxanthine
      CAS No.: 6136-37-4
      Chemical Name: 3,9-dihydro-1-methyl-1H-purine-2,6-dione
      Synonyms:1-甲基黄嘌呤
      分子量:166.14
      分子式:C₆H₆N₄O₂
      SMILES:O=C(N1C)NC2=C(N=CN2)C1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 1-Methylxanthine 是一种咖啡因衍生物,是咖啡因和茶碱 (1,3-二甲基黄嘌呤,TP) 在人体尿代谢产物。1-Methylxanthine 可增强肿瘤细胞的放射敏感性。
      IC50和靶点:
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    • Youn, H., Kook, Y.H., Oh, E.-T., et al.1-Methylxanthine enhances the radiosensitivity of tumor cellsInt. J. Radiat. Biol.85(2),167-174(2009)

      Rengelshausen, J., Lindenmaier, H., Cihlar, T., et al.Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthineBiochem. Biophys. Res. Commun.320(1),90-94(2004)

      González-Domínguez, R., Castellano-Escuder, P., Carmona, F., et al.Food and microbiota metabolites associate with cognitive decline in older subjects: A 12-year prospective studyMol. Nutr. Food Res.65(23),e2100606(2021)

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