Norharmane
Cat. No.：YN374078
| 产品名称: | Norharmane |
| CAS No.: | 244-63-3 |
| Chemical Name: | 9H-pyrido[3,4-b]indole |
| Synonyms: | 去甲哈尔满; Norharman; β-Carboline |
| 分子量: | 168.20 |
| 分子式: | C₁₁H₈N₂ |
| SMILES: | N1C2=C(C=CC=C2)C2=C1C=NC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Norharmane (Norharman) 可从咖啡中分离得到，是一种有效的选择性单胺氧化酶 A (MAO-A) 抑制剂，Ki为 3.34 μM。 |
| IC50和靶点: | [{name:"MAO-B:4.7 μM (IC50)'}, 'Microbial Metabolite', {'MAO-A:6.5 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Elfarra, A., et al.: Drug Metab. Dispos., 26, 779 (1998), Da Costa, A., et al.: Biocell, 23, 65 (1999), Janetzky, B., et al.: Drug Dev. Res., 46, 51 (1999), Kutty, R., et al.: Toxicol. Appl. Pharmacol., 107, 377 (1991), Riederer, F., et al.: J. Neurochem., 81, 814 (2002), Schott, Y., et al.: Bioorg. Med. Chem. Lett., 16, 5840 (2006)
