2'-Deoxyinosine
Cat. No.：YN374079
| 产品名称: | 2'-Deoxyinosine |
| CAS No.: | 890-38-0 |
| Chemical Name: | 1,9-Dihydro-9-(2’-deoxy-β-D-ribofuranosyl)-6H-purin-6-one; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one; Hypoxanthine Deoxyriboside; Didanosine EP Impurity C |
| Synonyms: | Deoxyinosine,2'-脱氧肌苷,Guanine deoxyriboside |
| 分子量: | 252.23 |
| 分子式: | C₁₀H₁₂N₄O₄ |
| SMILES: | OC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)C3)C2=NC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2’-deoxyadenosine 能够抑制人癌细胞株的生长，并发现其与嘌呤核苷磷酸化酶 (PNP) 缺乏有关。 |
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Lim, K.S., Jenner, A., and Halliwell, B.Quantitative gas chromatography mass spectrometric analysis of 2'-deoxyinosine in tissue DNANat. Protoc.1(4),1995-2002(2006)
Dong, M., Wang, C., Deen, W.M., et al.Absence of 2'-deoxyoxanosine and presence of abasic sites in DNA exposed to nitric oxide at controlled physiological concentrationsChem. Res. Toxicol.16(9),1044-1055(2003)
Ciccolini, J., Peillard, L., Evrard, A., et al.Enhanced antitumor activity of 5-fluorouracil in combination with 2'-deoxyinosine in human colorectal cell lines and human colon tumor xenograftsClin. Cancer Res.6(4),1529-1535(2000)
