Thymine
Cat. No.:YN374123
CAS No. :65-71-4
产品名称: | Thymine |
CAS No.: | 65-71-4 |
Chemical Name: | 5-methyl-2,4(1H,3H)-pyrimidinedione |
Synonyms: | 胸腺嘧啶,5-methyluracil |
分子量: | 126.11 |
分子式: | C₅H₆N₂O₂ |
SMILES: | O=C1NC(C(C)=CN1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Thymine 是 DNA 的四个碱基之一,在动物癌症模型中,可以作为5-氟尿嘧啶 (5-FU) 的靶标,其 Km值为 2.3 μM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
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Ghannam, J.Y., Wang, J., and Jan, A.Biochemistry, DNA Structure,1-5(2021)
Brown, N.S., and Bicknell, R.Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesisBiochem. J.334(Pt 1),1-8(1998)
Banoub, J.H., Newton, R.P., Esmans, E., et al.Recent developments in mass spectrometry for the characterization of nucleosides, nucleotides, oligonucleotides, and nucleic acidsChem. Rev.105(5),1869-1915(2005)