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8-Hydroxy-2'-deoxyguanosine

Cat. No.:YN374152

  • CAS No. :88847-89-6

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 8-Hydroxy-2'-deoxyguanosine
      CAS No.: 88847-89-6
      Chemical Name: 2'-deoxy-7,8-dihydro-8-oxo-guanosine
      Synonyms:8-Oxo-2'-deoxyguanosine,8-Oxo-dG,2'-Deoxy-8-oxoguanosine,8 Oxo dG,8-OHdG,8-Hydroxydeoxyguanosine,8-OH-脱氧鸟嘌呤,8-Hydroxy-2-Deoxyguanosine,8 OHdG
      分子量:283.24
      分子式:C₁₀H₁₃N₅O₅
      SMILES:NC1=NC(C(NC2=O)=C(N2[C@H]3C[C@H](O)[C@H](O3)CO)N1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 8-Hydroxy-2'-deoxyguanosine 是氧化应激和致癌反应的关键生物标志物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Floyd, R.A.Role of oxygen free radicals in carcinogenesis and brain ischemiaFASEB J.4(9),2587-2597(1990)

      Beckman, K.B., and Ames, B.N.Oxidative decay of DNAJ. Biol. Chem.272(32),19633-19636(1997)

      Spencer, J.P.E., Jenner, A., Chimel, K., et al.DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cellsFEBS Lett.374(2),233-236(1995)

      Epe, B., Ballmaier, D., Roussyn, I., et al.DNA damage by peroxynitrite characterized with DNA repair enzymesNucleic Acids Res.24(21),4105-4110(1996)

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