Potassium 1H-indol-3-yl sulfate
Cat. No.:YN374160
CAS No. :2642-37-7
产品名称: | Potassium 1H-indol-3-yl sulfate |
CAS No.: | 2642-37-7 |
Chemical Name: | 1H-indol-3-ol, 3-(hydrogen sulfate), monopotassium salt |
Synonyms: | 硫酸吲哚钾盐,Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate |
分子量: | 251.30 |
分子式: | C₈H₆KNO₄S |
SMILES: | O=S(OC1=CNC2=C1C=CC=C2)([O-])=O.[K+] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Potassium 1H-indol-3-yl sulfate 是一种内源性代谢产物。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Niwa, T.Uremic toxicity of indoxyl sulfateNagoya J. Med. Sci.72(1-2),1-11(2010)
Banoglu, E., and King, R.S.Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfateEur. J. Drug Metab. Pharmacokinet.27(2),135-140(2002)
Schroeder, J.C., Dinatale, B.C., Murray, I.A., et al.The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptorBiochemistry49(2),393-400(2010)
Enomoto, A., Takeda, M., Tojo, A., et al.Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicityJ. AM. Soc. Nephrol.13(7),1711-1720(2002)
Pieniazek, A., Gwozdzinski, L., Hikisz, P., et al.Indoxyl sulfate generates free radicals, decreases antioxidant defense, and leads to damage to mononuclear blood cellsChem. Res. Toxicol.31(9),869-875(2018)