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Dihydrouracil

Cat. No.:YN374190

  • CAS No. :504-07-4

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    • 产品名称: Dihydrouracil
      CAS No.: 504-07-4
      Chemical Name: dihydro-2,4(1H,3H)-pyrimidinedione
      Synonyms:二氢尿嘧啶; 5,6
      分子量:114.10
      分子式:C₄H₆N₂O₂
      SMILES:O=C1CCNC(N1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Dihydrouracil (5,6-Dihydrouracil),尿嘧啶的代谢产物,可作为鉴定二氢嘧啶脱氢酶 (DPD) 缺陷的标志物。
      IC50和靶点:
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    • Büchel, B., Rhyn, P., Schürch, S., et al.LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patientsBiomed. Chromatogr.27(1),7-16(2013)

      Chavani, O., Jensen, B.P., Strother, R.M., et al.Development, validation and application of a novel liquid chromatography tandem mass spectrometry assay measuring uracil, 5,6-dihydrouracil, 5-fluorouracil, 5,6-dihydro-5-fluorouracil, α-fluoro-β-ureidopropionic acid and α-fluoro-β-alanine in human plasmaJ. Pharm. Biomed. Anal.142,125-135(2017)

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